GOx signaling triggered by aptamer-based ATP detection

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GOx signaling triggered by aptamer-based ATP detection.

Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to 'turn-on' the activity of apo-GOx and thus generates a measurable response.

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ژورنال

عنوان ژورنال: Chemical Communications

سال: 2012

ISSN: 1359-7345,1364-548X

DOI: 10.1039/c2cc34279k